Structure of PDB 3keq Chain A

Receptor sequence
>3keqA (length=196) Species: 216495 (Streptococcus agalactiae serogroup III) [Search protein sequence]
SIPKATAKRLSLYYRIFKRFNTDGIEKASSKQIADALGIDSATVRRDFSY
FGEYDVKKLMNFFAEILNTTNVMLVGCGNIGRALLHYRFHDRNKMQISMA
FDLDSNDLVGKTTEDGIPVYGISTINDHLIDSDIETAILTVPSTEAQEVA
DILVKAGIKGILSFSPVHLTLPKDIIVQYVDLTSELQTLLYFMNQQ
3D structure
PDB3keq NAD+ pool depletion as a signal for the Rex regulon involved in Streptococcus agalactiae virulence.
ChainA
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A G93 N94 I95 D117 L118 I137 V156 P157 S158 V164 F179 S180 G78 N79 I80 D102 L103 I122 V141 P142 S143 V149 F164 S165
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0051775 response to redox state
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3keq, PDBe:3keq, PDBj:3keq
PDBsum3keq
PubMed34370789
UniProtQ8E565|REX_STRA3 Redox-sensing transcriptional repressor Rex (Gene Name=rex)

[Back to BioLiP]