Structure of PDB 3k9x Chain A

Receptor sequence
>3k9xA (length=86) Species: 9606 (Homo sapiens) [Search protein sequence]
CETSPCQNQGKCKDEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHE
EQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLE
3D structure
PDB3k9x Aroylguanidine-based factor Xa inhibitors: the discovery of BMS-344577
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.6: coagulation factor Xa.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MBM A Q96 N120 Q7 N28 BindingDB: IC50=4nM
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:3k9x, PDBe:3k9x, PDBj:3k9x
PDBsum3k9x
PubMed19896847
UniProtP00742|FA10_HUMAN Coagulation factor X (Gene Name=F10)

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