Structure of PDB 3k8c Chain A

Receptor sequence
>3k8cA (length=152) Species: 353153 (Trypanosoma cruzi strain CL Brener) [Search protein sequence]
MTRRVAIGTDHPAFAIHENLILYVKEAGDEFVPVYCGPKTAESVDYPDFA
SRVAEMVARKEVEFGVLACGSGIGMSIAANKVPGVRAALCHDHYTAAMSR
IHNDANIVCVGERTTGVEVIREIIITFLQTPFSGEERHVRRIEKIRAIEA
SH
3D structure
PDB3k8c Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family.
ChainA
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D10 C69 S71 H102 H138
Catalytic site (residue number reindexed from 1) D10 C69 S71 H102 H138
Enzyme Commision number 5.3.1.6: ribose-5-phosphate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RES A D10 H11 C69 G70 S71 G74 D10 H11 C69 G70 S71 G74 PDBbind-CN: -logKd/Ki=2.92,Ki=1.2mM
BS02 RES A H102 N103 R137 R141 H102 N103 R137 R141 PDBbind-CN: -logKd/Ki=2.92,Ki=1.2mM
Gene Ontology
Molecular Function
GO:0016853 isomerase activity
GO:0042802 identical protein binding
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3k8c, PDBe:3k8c, PDBj:3k8c
PDBsum3k8c
PubMed21205211
UniProtQ4CQE2

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