Structure of PDB 3k6p Chain A

Receptor sequence
>3k6pA (length=226) Species: 9606 (Homo sapiens) [Search protein sequence]
HHLEVLFQGPVNALVSHLLVVEPEKLYAMPHLPAVATLCDLFDREIVVTI
SWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDL
VLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSV
HIEDAEAVEQLREALHEALLEYEAGRGGAERRAGRLLLTLPLLRQTAGKV
LAHFYGVLEGKVPMHKLFLEMLEAMM
3D structure
PDB3k6p Development of Diaryl Ether based ligands for Estrogen Related Receptor alpha as Potential Anti-Diabetic Agents.
ChainA
Resolution1.996 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 5FB A L324 C325 F328 E331 V369 F382 L398 F495 V504 M506 L38 C39 F42 E45 V83 F96 L112 F204 V212 M214
External links
PDB RCSB:3k6p, PDBe:3k6p, PDBj:3k6p
PDBsum3k6p
PubMed
UniProtP11474|ERR1_HUMAN Steroid hormone receptor ERR1 (Gene Name=ESRRA)

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