Structure of PDB 3k5e Chain A

Receptor sequence
>3k5eA (length=329) Species: 9606 (Homo sapiens) [Search protein sequence]
NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGDKSSRKTYTFD
MVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGER
SPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELF
DLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAA
KRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGS
ENNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIA
TISPASLNLEETLSTLEYAHRAKNILNKP
3D structure
PDB3k5e The structure of human kinesin-like motor protein Kif11/KSP/Eg5 in complex with ADP and enastrol.
ChainA
Resolution1.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.4: Transferred entry: 5.6.1.3.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 K5E A E116 E118 R119 D130 A133 I136 P137 Y211 E97 E99 R100 D111 A114 I117 P118 Y192
BS02 ADP A R24 P27 T107 G108 T109 G110 K111 T112 F113 E118 R7 P10 T88 G89 T90 G91 K92 T93 F94 E99
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:3k5e, PDBe:3k5e, PDBj:3k5e
PDBsum3k5e
PubMed
UniProtP52732|KIF11_HUMAN Kinesin-like protein KIF11 (Gene Name=KIF11)

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