Structure of PDB 3k3g Chain A

Receptor sequence
>3k3gA (length=331) Species: 882 (Nitratidesulfovibrio vulgaris str. Hildenborough) [Search protein sequence]
RAFGEQLLKNPLIEFCDSVCRGCGQVMFQNNTVTGLLFFAGIFYNSTTLG
VCAVLGTAASTLTAQLLGVDKPLVRAGLFGFNGTLAGIALPFFFNYEPAM
LGYVALNGAFTTIIMASLLNFLGKWGVPALTAPFVLATWLLMFGVYKLSL
FHPGALIAPALPSVDMGTVTGRTFMEGLFKGVGEVMFQDNIVTGVIFVVA
ILVNSRISALFAVIGSLVGLCTALIMHSPETPVRLGLYGFNSVLCGIAMG
GIFFYLNIRTFLYALGCMVLGAIATGAFSVLLSPIGMPALTWPFIVVTWL
FLFAGSMFRNIAQVPTEKAGTPEDNLRSLAI
3D structure
PDB3k3g Crystal structure of a bacterial homologue of the kidney urea transporter.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MMU A E187 F190 F243 E184 F187 F240 MOAD: ic50=1.4mM
PDBbind-CN: -logKd/Ki=2.85,IC50=1.4mM
BS02 MMU A Q24 V25 F27 F80 Q25 V26 F28 F81 MOAD: ic50=1.4mM
PDBbind-CN: -logKd/Ki=2.85,IC50=1.4mM
Gene Ontology
Molecular Function
GO:0015204 urea transmembrane transporter activity
GO:0015265 urea channel activity
GO:0033219 urea binding
GO:0042802 identical protein binding
Biological Process
GO:0070207 protein homotrimerization
GO:0071918 urea transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:3k3g, PDBe:3k3g, PDBj:3k3g
PDBsum3k3g
PubMed19865084
UniProtQ72CX3|UT_NITV2 Urea transporter DVU1160 (Gene Name=DVU_1160)

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