Structure of PDB 3jzp Chain A

Receptor sequence
>3jzpA (length=87) Species: 9606 (Homo sapiens) [Search protein sequence]
QINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQH
MVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTL
3D structure
PDB3jzp Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX.
ChainA
Resolution1.74 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A M53 G57 I60 M61 Y66 Q71 H72 V92 K93 L98 Y99 M31 G35 I38 M39 Y44 Q49 H50 V70 K71 L76 Y77
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3jzp, PDBe:3jzp, PDBj:3jzp
PDBsum3jzp
PubMed19910468
UniProtO15151|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)

[Back to BioLiP]