Structure of PDB 3juk Chain A

Receptor sequence
>3jukA (length=265) Species: 85962 (Helicobacter pylori 26695) [Search protein sequence]
MIKKCLFPAAGYGTRFLPITKTIPKEMLPIVDKPLIQYAVEEAMEAGCEV
MAIVTGRNKRSLEDYFDTSYTNKENALKSIRNIIEKCCFSYVRQKQMKGL
GHAILTGEALIGNEPFAVILADDLCISHDHPSVLKQMTSLYQKYQCSIVA
IEEVALEEVSKYGVIRGEWLEEGVYEIKDMVEKPNQEDAPSNLAVIGRYI
LTPDIFEILSETKPGKNNEIQITDALRTQAKRKRIIAYQFKGKRYDCGSV
EGYIEASNAYYKKRL
3D structure
PDB3juk Structural basis for the reaction mechanism of UDP-glucose pyrophosphorylase
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.9: UTP--glucose-1-phosphate uridylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UPG A A10 G11 E26 Q102 M105 G107 L108 A111 D131 Y170 G171 E190 K191 V203 A10 G11 E26 Q94 M97 G99 L100 A103 D123 Y162 G163 E182 K183 V195 PDBbind-CN: -logKd/Ki=4.89,Kd=12.9uM
Gene Ontology
Molecular Function
GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006011 UDP-glucose metabolic process
GO:0009058 biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3juk, PDBe:3juk, PDBj:3juk
PDBsum3juk
PubMed20238176
UniProtO25363

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