Structure of PDB 3jb6 Chain A

Receptor sequence
>3jb6A (length=1196) Species: 110829 (Bombyx mori cypovirus 1) [Search protein sequence]
TKLHNTIFSETRKFTRESFKEIEHLTARLANDRVARHDFLFNTSIVLISD
YSGEDSNGNQLQATITIPNEIINPKEYDPSDYPLAEDESFFKQGHKYDYL
VTFRAGSLTNTYEPKTKMYKLHAALDKLMHVKQRKSRFADLWRELCAVIA
SLDVWYQTTNYPLRTYVKLLFHKGDEFPFYESPSQDRIIFNDKSVASILP
TFVYTCCQVGTAIMSGILTHVESIVAMNHFLHCAKDSYIDEKLKIKGIGR
SWYQEALHNVCQATVPVWSQFNEVIGHRTKSTSEPHFVSSTFISLRAKRA
ELLYPEFNAYINRAIQLSKTQNDVANYYAACRAMTNDGTFLATLTELSLD
AAVFPRIEQHLVTRPAVLMSNTRHESLKQKYTNGVGSIAQSYLSSFTDEI
AKRVNGRHHDEAWLNFLTTSRIVMQAVFAREYRTPERIFKSLKAPIKLVE
RQQSDRRQRAISGLDNDRLFLSFMPYTIGKQIYELNDNAAQGKQAGNAFD
IGEMLYWTSQRNVLLSSIDVAGMDASVTTNTKDIYNTFVLDVASKCTVPR
FGPYYAKNMEVFEAGNRQSQVRYVNAAWQACALEAANSQTSTSYESEIFG
QVKNAEGTYPSGRADTSTHHTVLLQGLVRGNELKRASDGKNSCLATIKIL
GDDIMEIFQGSESDTYDHAVSNASILNESGFATTAELSQNSIVLLQQLVV
NGTFWGFADRISLWTREDTKDIGRLNLAMMELNALIDDLVFRVRRPEGLK
MLGFFCGAICLRRFTLSVDNKLYDSTYNNLSKYMTLTKYDKNPDSDSTLM
SLILPLAWLFMPRGGEYPAYPFERRDGTFTEDESMFTARGAYKRRLLYDV
SNIGEMIQQNSMALDDDLLHEYGFTGALLLIDLNILDLIDEVKKEDISPV
KVSELATSLEQLGKLGEREKSRRAASDLKIRGHALSNDIVYGYGLQEKIQ
KSAMATKETTVQSKRVSSRLHDVIVAKTRDYKISTIPADALHLHEFEVED
VTVDLLPHAKHTSYSSLAYNMSFGSDGWFAFALLGGLDRSANLLRLDVAS
IRGNYHKFSYDDPVFKQGYKIYKSDATLLNDFFTAISAGPKEQGILLRAF
AYYSLYGNVEYHYVLSPRQLFFLSDNPVSAERLVRIPPKYYVSTQCRALY
NIFSYLHILRSIANNRGKRLKMVLHPGLIAYVRGTSQGAILPEADN
3D structure
PDB3jb6 In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus.
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A A370 T386 N594 A366 T382 N566
BS02 peptide A D1032 L1033 A1037 K1038 F1051 G1052 S1053 D1054 W1056 I1190 A1191 N1193 R1194 D1004 L1005 A1009 K1010 F1023 G1024 S1025 D1026 W1028 I1162 A1163 N1165 R1166
BS03 GTP A R37 D144 R147 Y184 R33 D140 R143 Y180
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0019079 viral genome replication

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Molecular Function

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Biological Process
External links
PDB RCSB:3jb6, PDBe:3jb6, PDBj:3jb6
PDBsum3jb6
PubMed26503045
UniProtD0EZK6

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