Structure of PDB 3ixa Chain A

Receptor sequence
>3ixaA (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAP
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB3ixa T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A M5 Y7 F9 M45 E63 K66 V67 H70 T73 V76 D77 Y84 Y99 Y116 T143 K146 W147 Q155 L156 Y159 W167 Y171 M5 Y7 F9 M45 E63 K66 V67 H70 T73 V76 D77 Y84 Y99 Y116 T143 K146 W147 Q155 L156 Y159 W167 Y171
External links
PDB RCSB:3ixa, PDBe:3ixa, PDBj:3ixa
PDBsum3ixa
PubMed20064447
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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