Structure of PDB 3iuy Chain A

Receptor sequence
>3iuyA (length=213) Species: 9606 (Homo sapiens) [Search protein sequence]
MTCDDLKSGEKRLIPKPTCRFKDAFQQYPDLLKSIIRVGILKPTPIQSQA
WPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDNGPGMLVLTPTRELALH
VEAECSKYSYKGLKSICIYGQIEDISKGVDIIIATPGRLNDLQMNNSVNL
RSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATWPDTVRQL
ALSYLKDPMIVYV
3D structure
PDB3iuy Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AMP A I251 Q258 G278 G280 K281 T282 L283 H320 E324 I40 Q47 G67 G69 K70 T71 L72 H100 E104
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:3iuy, PDBe:3iuy, PDBj:3iuy
PDBsum3iuy
PubMed20941364
UniProtQ86TM3|DDX53_HUMAN Probable ATP-dependent RNA helicase DDX53 (Gene Name=DDX53)

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