Structure of PDB 3it6 Chain A

Receptor sequence
>3it6A (length=193) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
TTRLLRAQGVTAPAGFRAAGVAAGIKASGALDLALVFNEGPDYAAAGVFT
RNQVKAAPVLWTQQVLTTGRLRAVILNSGGANACTGPAGFADTHATAEAV
AAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVAHVVHEMHGGLVG
GDEAAHAIMTTDNVPKQVALHHHDNWTVGGMAKGAGMLAPSLA
3D structure
PDB3it6 The molecular structure of ornithine acetyltransferase from Mycobacterium tuberculosis bound to ornithine, a competitive inhibitor.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.1: amino-acid N-acetyltransferase.
2.3.1.35: glutamate N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ORN A T166 M193 T160 M187
Gene Ontology
Molecular Function
GO:0004358 glutamate N-acetyltransferase activity
Biological Process
GO:0006526 L-arginine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3it6, PDBe:3it6, PDBj:3it6
PDBsum3it6
PubMed20184895
UniProtP9WPZ3|ARGJ_MYCTU Arginine biosynthesis bifunctional protein ArgJ (Gene Name=argJ)

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