Structure of PDB 3inr Chain A

Receptor sequence

>3inrA (length=383) Species: 573 (Klebsiella pneumoniae) [Search protein sequence]

KSKKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHIGGNSYDARDSETN
VMVHVYGPHIFHTDNETVWNYINKHAEMMPYVNRVKATVNGQVFSLPINL
HTINQFFSKTCSPDEARALIAEKGDSTIADPQTFEEQALRFIGKELYEAF
FKGYTIKQWGMQPSELPASILKRLPVRFNYDDNYFNHKFQGMPKCGYTQM
IKSILNHENIKVDLQREFIVDERTHYDHVFYSGPLDAFYGYQYGRLGYRT
LDFKKFIYQGDYQGCAVMNYCSVDVPYTRITEHKYFSPWEQHDGSVCYKE
YSRACEENDIPYYPIRQMGEMALLEKYLSLAENETNITFVGRLGTYRYLD
MDVTIAEALKTAEVYLNSLTDNQPMPVFTVSVG

3D structure

PDB

3inr X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin .

Chain

Resolution

2.3 Å

3D
structure

Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Catalytic site (original residue number in PDB)	R174 R178 R250 R280 E301 Y349 D351
Catalytic site (residue number reindexed from 1)	R173 R177 R249 R279 E300 Y348 D350
Enzyme Commision number	5.4.99.9: UDP-galactopyranose mutase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	V9 G10 G12 S14 D33 Q34 R35 G40 N41 P59 H60 I61 F219 G234 Y313 R343 Y349 L350 D351 M352 T355	V8 G9 G11 S13 D32 Q33 R34 G39 N40 P58 H59 I60 F218 G233 Y312 R342 Y348 L349 D350 M351 T354
BS02	GDU	A	F152 Y155 T156 W160 L175 Y185 N270 Y349 D351	F151 Y154 T155 W159 L174 Y184 N269 Y348 D350

Gene Ontology

	Molecular Function
GO:0008767	UDP-galactopyranose mutase activity

View graph for
Molecular Function

External links

PDB	RCSB:3inr, PDBe:3inr, PDBj:3inr
PDBsum	3inr
PubMed	19719175
UniProt	Q48485\|GLF1_KLEPN UDP-galactopyranose mutase (Gene Name=rfbD)

[Back to BioLiP]