Structure of PDB 3in1 Chain A

Receptor sequence

>3in1A (length=312) Species: 83333 (Escherichia coli K-12)

NLDVICIGAAIVDIPLQPVSKNIFDVDSYPLERIAMTTGGDAINEATIIS
RLGHRTALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLV
TEDGERTFVTNRNGSLWKLNIDDVDFARFSQAKLLSLASIFNSPLLDGKA
LTEIFTQAKARQMIICADMIKPRLNETLDDICEALSYVDYLFPNFAEAKL
LTGKETLDEIADCFLACGVKTVVIKTGKDGCFIKRGDMTMKVPAVAGITA
IDTIGAGDNFASGFIAALLEGKNLRECARFANATAAISVLSVGATTGVKN
RKLVEQLLEEYE

3D structure

• PDB: 3in1 Crystal structure of a putative Ribokinase in complex with ADP from E.coli
• Chain: A
• Resolution: 2.15 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): R108 G257 A258 G259 D260
• Catalytic site (residue number reindexed from 1): R106 G255 A256 G257 D258
• Enzyme Commision number: 2.7.1.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ADP	A	N196 K227 G229 G232 A246 T255 N284 A287	N194 K225 G227 G230 A244 T253 N282 A285

Gene Ontology

Molecular Function

• GO:0008673 2-dehydro-3-deoxygluconokinase activity
• GO:0016301 kinase activity
• GO:0016772 transferase activity, transferring phosphorus-containing groups
• GO:0019200 carbohydrate kinase activity
• GO:0042803 protein homodimerization activity

Biological Process

• GO:0006974 DNA damage response
• GO:0016310 phosphorylation
• GO:0019698 D-galacturonate catabolic process
• GO:0042840 D-glucuronate catabolic process
• GO:0046835 carbohydrate phosphorylation

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:3in1, PDBe:3in1, PDBj:3in1
• PDBsum: 3in1
• UniProt: P77493|YDJH_ECOLI Uncharacterized sugar kinase YdjH (Gene Name=ydjH)