Structure of PDB 3imd Chain A

Receptor sequence
>3imdA (length=101) Species: 9606 (Homo sapiens) [Search protein sequence]
MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGND
VQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQV
P
3D structure
PDB3imd Thermodynamic and Structural Effects of Conformational Constraints in Protein-Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization.
ChainA
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FYQ A R67 R86 S88 S90 S96 H107 F108 K109 L120 W121 R13 R32 S34 S36 S42 H53 F54 K55 L66 W67 MOAD: Ka=560000M^-1
BS02 MG A H58 N129 D133 H4 N75 D79
External links
PDB RCSB:3imd, PDBe:3imd, PDBj:3imd
PDBsum3imd
PubMed19886660
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

[Back to BioLiP]