Structure of PDB 3il2 Chain A

Receptor sequence
>3il2A (length=204) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence]
GMKVPEAAISRLITYLRILEELEAQGVHRTSSEQLGELAQVTAFQVRKDL
SYFGSYGTGYTVPVLKRELRHILGLNRKWGLCIVGMGDLGSALADYPGFG
ESFELRGFFDVDPEKVGRPVRGGVIEHVDLLPQRVPGRIEIALLTVPREA
AQKAADLLVAAGIKGILNFAPVVLEVPKEVAVENVDFLAGLTRLSFAILN
PKWR
3D structure
PDB3il2 Structural basis for NADH/NAD+ redox sensing by a Rex family repressor.
ChainA
Resolution2.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A S30 S31 R46 K47 S54 G56 Y62 S31 S32 R47 K48 S55 G57 Y60
BS02 dna A P4 R10 F43 Q44 K47 P5 R11 F44 Q45 K48
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0051775 response to redox state
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3il2, PDBe:3il2, PDBj:3il2
PDBsum3il2
PubMed20513431
UniProtQ72I39|REX_THET2 Redox-sensing transcriptional repressor Rex (Gene Name=rex)

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