Structure of PDB 3ijl Chain A

Receptor sequence
>3ijlA (length=336) Species: 818 (Bacteroides thetaiotaomicron) [Search protein sequence]
KMTFFPYELKLRHVFTVATYSRTTTPDVQVEIEYEGVTGYGEASMPPYLG
ETVESVMNFLKKVNLEQFSDPFQLEDILSYVDSLSPKDTAAKAAVDIALH
DLVGKLLGAPWYKIWGLNKEKTPSTTFTIGIDTPDVVRAKTKECAGLFNI
LKVKLGRDNDKEMIETIRSVTDLPIAVDANQGWKDRQYALDMIHWLKEKG
IVMIEQPMPKEQLDDIAWVTQQSPLPVFADESLQRLGDVAALKGAFTGIN
IKLMKCTGMREAWKMVTLAHALGMRVMVGCMTETSCAISAASQFSPAVDF
ADLDGNLLISNDRFKGVEVVNGKITLNDLPGIGVMK
3D structure
PDB3ijl Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.
ChainA
Resolution1.5 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) F61 T174 L197 K198 K200 D224 N226 E251 D276 E277 K298 G325 C326 M327 D345 A347 D348 L349
Catalytic site (residue number reindexed from 1) F15 T128 L151 K152 K154 D178 N180 E205 D230 E231 K252 G279 C280 M281 D299 A301 D302 L303
Enzyme Commision number 5.1.1.20: L-Ala-D/L-Glu epimerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PRO A C326 D348 D350 L354 C280 D302 D304 L308
BS02 DGL A F61 V63 R68 P92 Y94 K298 C326 M327 F15 V17 R22 P46 Y48 K252 C280 M281
BS03 MG A D224 E251 D276 D178 E205 D230
Gene Ontology
Molecular Function
GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives

View graph for
Molecular Function
External links
PDB RCSB:3ijl, PDBe:3ijl, PDBj:3ijl
PDBsum3ijl
PubMed22392983
UniProtQ8A861|AEEP_BACTN L-Ala-D/L-Glu epimerase (Gene Name=BT_1313)

[Back to BioLiP]