Structure of PDB 3iie Chain A

Receptor sequence
>3iieA (length=389) Species: 502800 (Yersinia pseudotuberculosis YPIII) [Search protein sequence]
SNAMKQLTILGSTGSIGNSTLSVVRANPELFKVTALVAGRNVREMAQQCL
EFSPRYAAMSDEHSAKSLRLLLAEQGSDTEVYSGETAACELAALDDVDQV
MAAIVGIAGLPSTLAAIRAGKQVLLANKESLITCGKLFMDEVKRSRAQLL
PIDSEHNAIFQSLPERIQRQLGYSSLNENGVSRIILTGSGGPFRETPLSQ
FSDVTPDQARKISVDSATMMNKGLEYIEARWLFNASAEQIEVVLHPQSVI
HSMVRYHDGSILAQMGTPDMRTPIAHAMAYPMRVSSGVAPLDFCKVGALT
FTTPDYQRYPCLKLAIDACNAGQAATTALNAANEISVMAFLDSKIRFTDI
EVINRTVVEGLLLSEPTSVEEVLVIDRKARDVAAQVIAK
3D structure
PDB3iie X-ray crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase from Yersinia pestis.
ChainA
Resolution2.21 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.267: 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D150 E152 E231 D153 E155 E225
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0030145 manganese ion binding
GO:0030604 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GO:0046872 metal ion binding
GO:0070402 NADPH binding
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
GO:0051484 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3iie, PDBe:3iie, PDBj:3iie
PDBsum3iie
PubMed
UniProtB1JQG4|DXR_YERPY 1-deoxy-D-xylulose 5-phosphate reductoisomerase (Gene Name=dxr)

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