Structure of PDB 3icf Chain A

Receptor sequence
>3icfA (length=316) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
MSQEFISKMVNDLFLKGKYLPKKYVAAIISHADTLFRQEPSMVELENNST
PDVKISVCGDTHGQFYDVLNLFRKFGKVGPKHTYLFNGDFVDRGSWSCEV
ALLFYCLKILHPNNFFLNRGNHESDNMNKIYGFEDECKYKYSQRIFNMFA
QSFESLPLATLINNDYLVMHGGLPSDPSATLSDFKNIDRFAQPPRDGAFM
ELLWADPQEANGMGPSQRGHAFGPDITDRFLRNNKLRKIFRSHELRMGGV
QFEQKGKLMTVFSAPNYCDSQGNLGGVIHVVPGHGILQAGRNDDQNLIIE
TFEAVEHPDIKPMAYS
3D structure
PDB3icf Structure of Protein serine/threonine phosphatase from Saccharomyces cerevisiae with similarity to human phosphatase PP5
ChainA
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D249 H251 D278 D281 R282 N310 H311 H359 R407 H434
Catalytic site (residue number reindexed from 1) D60 H62 D89 D92 R93 N121 H122 H170 R218 H243
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A D278 N310 H359 H434 D89 N121 H170 H243
BS02 FE A D249 H251 D278 D60 H62 D89
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:3icf, PDBe:3icf, PDBj:3icf
PDBsum3icf
PubMed
UniProtP53043|PPT1_YEAST Serine/threonine-protein phosphatase T (Gene Name=PPT1)

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