Structure of PDB 3iaz Chain A

Receptor sequence
>3iazA (length=341) Species: 9913 (Bos taurus) [Search protein sequence]
YTRVVWCAVGPEEQKKCQQWSQQSGQNVTCATASTTDDCIVLVLKGEADA
LNLDGGYIYTAGKCGLVPVLAENRKSSKHSSLDCVLRPTEGYLAVAVVKK
ANEGLTWNSLKDKKSCHTAVDRTAGWNIPMGLIVNQTGSCAFDEFFSQSC
APGADPKSRLCALCAGDDQGLDKCVPNSKEKYYGYTGAFRCLAEDVGDVA
FVKNDTVWENTNGESTADWAKNLKREDFRLLCLDGTRKPVTEAQSCHLAV
APNHAVVSRSDRAAHVEQVLLHQQALFGKNGKNCPDKFCLFKSETKNLLF
NDNTECLAKLGGRPTYEEYLGTEYVTAIANLKKCSLEACAF
3D structure
PDB3iaz The structural basis for the prevention of nonsteroidal antiinflammatory drug-induced gastrointestinal tract damage by the C-lobe of bovine colostrum lactoferrin
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AIN A E659 G662 T663 E318 G321 T322 MOAD: Kd=330uM
BS02 FE A D395 Y433 Y526 H595 D54 Y92 Y185 H254
BS03 CO3 A D395 T459 R463 A465 Y526 H595 D54 T118 R122 A124 Y185 H254
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Cellular Component
External links
PDB RCSB:3iaz, PDBe:3iaz, PDBj:3iaz
PDBsum3iaz
PubMed20006955
UniProtP24627|TRFL_BOVIN Lactotransferrin (Gene Name=LTF)

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