Structure of PDB 3i77 Chain A

Receptor sequence
>3i77A (length=230) Species: 1911 (Streptomyces griseus) [Search protein sequence]
VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNN
TSITATGGVVDLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPIN
QPTLKIATTTAYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRS
SSSFILVANEMICAGYPDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSW
GYGCARPGYPGVYTEVSTFASAIASAARTL
3D structure
PDB3i77 Combinatorial Enzyme Design Probes Allostery and Cooperativity in the Trypsin Fold.
ChainA
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H57 D102 Q192 G193 D194 S195 G196
Catalytic site (residue number reindexed from 1) H42 D89 Q176 G177 D178 S179 G180
Enzyme Commision number 3.4.21.4: trypsin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D165 A177A M180 E230 D145 A158 M161 E215
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3i77, PDBe:3i77, PDBj:3i77
PDBsum3i77
PubMed20399789
UniProtP00775|TRYP_STRGR Trypsin (Gene Name=sprT)

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