Structure of PDB 3i59 Chain A

Receptor sequence
>3i59A (length=215) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
HMDEILARAGIFQGVEPSQLQPVDFPRGHTVFAEGEPGDRLYIIISGKVK
IGRRAPDENLLTIMGPSDMFGELSIFDPGPRTSSATTITEVRAVSMDRDA
LRSWIADRPEISEQLLRVLARRLRRTNNNLADLIFTDVPGRVAKQLLQLA
QRFGTQEGGALRVTHDLTQEEIAQLVGASRETVNKALADFAHRGWIRLEG
KSVLISDSERLARRA
3D structure
PDB3i59 Structural Insights into the Mechanism of the Allosteric Transitions of Mycobacterium tuberculosis cAMP Receptor Protein.
ChainA
Resolution2.29 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 N6R A F38 L69 F78 G79 E80 L81 S82 R89 T90 S91 R130 T134 N137 L141 F32 L61 F70 G71 E72 L73 S74 R81 T82 S83 R122 T126 N129 L133
BS02 N6S A N135 L138 N127 L130
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005515 protein binding
GO:0030552 cAMP binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3i59, PDBe:3i59, PDBj:3i59
PDBsum3i59
PubMed19740754
UniProtP9WMH3|CRPL_MYCTU CRP-like cAMP-activated global transcriptional regulator (Gene Name=crp)

[Back to BioLiP]