Structure of PDB 3i4z Chain A

Receptor sequence
>3i4zA (length=438) [Search protein sequence]
MKAANASSAEAYRVLSRAFRFDNEDQKLWWHSTAPMFAKMLETANYTTPC
QYQYLITYKECVIPSLGCYPTNSAPRWLSILTRYGTPFELSLNCSNSIVR
YTFEPINQHTGTDKDPFNTHAIWESLQHLLPLEKSIDLEWFRHFKHDLTL
NSEESAFLAHNDRLVGGTIRTQNKLALDLKDGRFALKTYIYPALKAVVTG
KTIHELVFGSVRRLAVREPRILPPLNMLEEYIRSRGSKSTASPRLVSCDL
TSPAKSRIKIYLLEQMVSLEAMEDLWTLGGRRRDASTLEGLSLVRELWDL
IQLSPGLKSYPAPYLPLGVIPDERLPLMANFTLHQNDPVPEPQVYFTTFG
MNDMAVADALTTFFERRGWSEMARTYETTLKSYYPHADHDKLNYLHAYIS
FSYRDRTPYLSVYLQSFETGDWAVAPDLSKTGVYYSGL
3D structure
PDB3i4z The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria
ChainA
Resolution1.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.34: 4-dimethylallyltryptophan synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BU2 A I80 L81 T82 A397 I80 L81 T82 A397
BS02 BU2 A Y376 Y383 Y376 Y383
BS03 BU2 A D322 E323 D322 E323
BS04 BU2 A Y84 L317 G318 Y84 L317 G318
BS05 BU2 A P326 Y398 P326 Y398
Gene Ontology
Molecular Function
GO:0004659 prenyltransferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0050364 tryptophan dimethylallyltransferase activity
Biological Process
GO:0009820 alkaloid metabolic process
GO:0035835 indole alkaloid biosynthetic process
GO:0035837 ergot alkaloid biosynthetic process
GO:1900809 fumigaclavine C biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3i4z, PDBe:3i4z, PDBj:3i4z
PDBsum3i4z
PubMed19706516
UniProtQ50EL0|DMAW_ASPFU Tryptophan dimethylallyltransferase (Gene Name=dmaW)

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