Structure of PDB 3i1h Chain A

Receptor sequence
>3i1hA (length=142) Species: 9606 (Homo sapiens) [Search protein sequence]
CEFGYIYRLAQDYLQCVLQIPPSKTSRVLQNVAFSVQKEVEKNLKSCLDN
VNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQI
APDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEP
3D structure
PDB3i1h crystal structure of human BFL-1 in complex with BAK BH3 peptide
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A V48 L52 C55 V74 K77 E78 D81 N85 G87 R88 T91 F95 K147 V40 L44 C47 V66 K69 E70 D73 N77 G79 R80 T83 F87 K139
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:3i1h, PDBe:3i1h, PDBj:3i1h
PDBsum3i1h
PubMed
UniProtQ16548|B2LA1_HUMAN Bcl-2-related protein A1 (Gene Name=BCL2A1)

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