Structure of PDB 3hu6 Chain A

Receptor sequence
>3hu6A (length=284) Species: 9606 (Homo sapiens) [Search protein sequence]
SKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSKLKWCLRVNPKGLDSKD
YLSLYLLLVSCPKEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGF
KKFIRRGFLLDEANGLLPDDKLTLFCEVSVVQDSQTMNMVKVPECRLADE
LGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHKNRVEIND
VEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCS
NLSVENAAEILILADLHSADQLKTQAVDFINYHA
3D structure
PDB3hu6 Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R70 Y87 Y123 K129 D130 W131 G132 F133 R40 Y55 Y90 K96 D97 W98 G99 F100
External links
PDB RCSB:3hu6, PDBe:3hu6, PDBj:3hu6
PDBsum3hu6
PubMed19818708
UniProtO43791|SPOP_HUMAN Speckle-type POZ protein (Gene Name=SPOP)

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