Structure of PDB 3hs8 Chain A

Receptor sequence
>3hs8A (length=238) Species: 10090 (Mus musculus) [Search protein sequence]
FEDNFARFVCKNNGVLFENQLLQIGLKSEFRQNLGRMFIFYGNKTSTQFL
NFTPTLICADDLQTNLNLQTKPVDPTVDGGAQVQQVVNIECISDFTEAPV
LNIQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRWKQLSNPQQEV
QNIFKAKHPMDTEITKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQI
GCLLRLEPNLQAQMYRLTLRTSKDTVSQRLCELLSEQF
3D structure
PDB3hs8 Regulation of synaptic vesicle recycling by complex formation between intersectin 1 and the clathrin adaptor complex AP2.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A E702 V715 E718 G725 L726 K727 F740 G742 N743 G780 A781 Q782 E2 V15 E18 G25 L26 K27 F40 G42 N43 G80 A81 Q82
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030117 membrane coat
GO:0030131 clathrin adaptor complex

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Biological Process

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Cellular Component
External links
PDB RCSB:3hs8, PDBe:3hs8, PDBj:3hs8
PDBsum3hs8
PubMed20160082
UniProtP17427|AP2A2_MOUSE AP-2 complex subunit alpha-2 (Gene Name=Ap2a2)

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