Structure of PDB 3hr4 Chain A

Receptor sequence
>3hr4A (length=189) Species: 9606 (Homo sapiens) [Search protein sequence]
REIPLKVLVKAVLFACMLMRKTMASRVRVTILFATETGKSEALAWDLGAL
FSCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPGNGEKLKKSLF
MLKELNNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGD
ELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYT
3D structure
PDB3hr4 Regulation of Interdomain Interactions by CaM in Inducible Nitric Oxide Synthase
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.39: nitric-oxide synthase (NADPH).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN A T545 E546 T547 G548 K549 S550 S591 T592 F593 G594 G627 S628 Y631 R633 F634 C635 E661 T35 E36 T37 G38 K39 S40 S81 T82 F83 G84 G117 S118 Y121 R123 F124 C125 E151
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3hr4, PDBe:3hr4, PDBj:3hr4
PDBsum3hr4
PubMed
UniProtP35228|NOS2_HUMAN Nitric oxide synthase, inducible (Gene Name=NOS2)

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