Structure of PDB 3hqt Chain A

Receptor sequence
>3hqtA (length=385) Species: 666 (Vibrio cholerae) [Search protein sequence]
QLPDFIQNKIDHYIENYFDINKNGKHLVLGKQASPDDIILQSNDYLALAN
HPLIKARLAKSLLEEQQSLFMSASFLQNDYDKPMIEKRLAKFTGFDECLL
SQSGWNANVGLLQTICQPNTNVYIDFFAHMSLWEGARYANAQAHPFMHNN
CDHLRMLIQRHGPGIIVVDSIYSTLGTIAPLAELVNISKEFGCALLVDES
HSLGTHGPNGAGLLAELGLTREVHFMTASLAKTFAYRAGAIWCNNEVNRC
VPFISYPAIFSSTLLPYEAAGLETTLEIIESADNRRQHLDRMARKLRIGL
SQLGLTIRSESQIIGLETGDERNTEKVRDYLESNGVFGSVFCRPATSKNK
NIIRLSLNSDVNDEQIAKIIEVCSDAVNYGDFYFR
3D structure
PDB3hqt The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA.
ChainA
Resolution2.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N47 H133 D173 S177 D202 H205 K236
Catalytic site (residue number reindexed from 1) N43 H129 D169 S173 D198 H201 K232
Enzyme Commision number 2.3.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A S107 G108 W109 H133 D202 S204 H205 S233 K236 S103 G104 W105 H129 D198 S200 H201 S229 K232
BS02 PLP A F264 S265 S266 F260 S261 S262
Gene Ontology
Molecular Function
GO:0008483 transaminase activity
GO:0008710 8-amino-7-oxononanoate synthase activity
GO:0016746 acyltransferase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0008150 biological_process
GO:0009058 biosynthetic process
GO:0009102 biotin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3hqt, PDBe:3hqt, PDBj:3hqt
PDBsum3hqt
PubMed19838203
UniProtQ9KM65|CQSA_VIBCH CAI-1 autoinducer synthase (Gene Name=cqsA)

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