Structure of PDB 3hko Chain A

Receptor sequence
>3hkoA (length=319) Species: 353152 (Cryptosporidium parvum Iowa II) [Search protein sequence]
LYFQGGSLLELQKKYHLKGAIGQGSYGVVRVAIENQTRAIRAIKIMNKNK
IRQKDVERIKTEVRLMKKLHHPNIARLYEVYEDEQYICLVMELCHGGHLL
DKLNVFIDDSTGKCAMDVVKTQICPCPECNEEAINGSIFRESLDFVQREK
LISNIMRQIFSALHYLHNQGICHRDIKPENFLFSTNKSFEIKLVDFGLSK
EFYKLNNGAGTPYFVAPEVLNTTNESYGPKCDAWSAGVLLHLLLMGAVPF
PGVNDADTISQVLNKKLCFENPNYNVLSPLARDLLSNLLNRNVDERFDAM
RALQHPWISQFSDKIYKMS
3D structure
PDB3hko Crystal structure of a cdpk kinase domain from cryptosporidium Parvum, cgd7_40
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D175 K177 N180 D195 T219
Catalytic site (residue number reindexed from 1) D175 K177 N180 D195 T211
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H93 C122 C124 C127 H95 C124 C126 C129
BS02 ANP A Q18 G19 S20 E90 C92 H96 L182 Q23 G24 S25 E92 C94 H98 L182
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:3hko, PDBe:3hko, PDBj:3hko
PDBsum3hko
PubMed
UniProtQ5CZ29

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