Structure of PDB 3hik Chain A

Receptor sequence
>3hikA (length=224) Species: 9606 (Homo sapiens) [Search protein sequence]
DCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDK
YGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPN
SLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSA
IILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEY
GCCKELASRLRYARTMVDKLLSSR
3D structure
PDB3hik Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.
ChainA
Resolution1.77 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A W414 D416 Y485 L490 R516 F535 H538 K540 W44 D46 Y115 L120 R146 F165 H168 K170
External links
PDB RCSB:3hik, PDBe:3hik, PDBj:3hik
PDBsum3hik
PubMed19597481
UniProtP53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)

[Back to BioLiP]