Structure of PDB 3hcv Chain A

Receptor sequence
>3hcvA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFHTSVSRPGRGEPRFITVGYVDDTLFVRFDSDAASPREEPRAP
WIEQEGPEYWDRETQICKAKAQTDREDLRTLLRYYNQSEAGSHTLQNMYG
CDVGPDGRLLRGYHQHAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB3hcv Citrullination-and mhc polymorphism-dependent conformational changes of a self peptide
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 T24 E45 R62 E63 I66 C67 K70 T73 D77 L81 Y84 Y99 H116 T143 K146 W147 V152 Q155 Y159 E163 W167 Y171 Y7 T24 E45 R62 E63 I66 C67 K70 T73 D77 L81 Y84 Y99 H116 T143 K146 W147 V152 Q155 Y159 E163 W167 Y171
External links
PDB RCSB:3hcv, PDBe:3hcv, PDBj:3hcv
PDBsum3hcv
PubMed
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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