Structure of PDB 3h87 Chain A

Receptor sequence
>3h87A (length=136) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
TDQRWLIDKSALVRLTDSPDMEIWSNRIERGLVHITGVTRLEVGFSAECG
EIARREFREPPLSAMPVEYLTPRIEDRALEVQTLLADRGHHRGPSIPDLL
IAATAELSGLTVLHVDKDFDAIAALTGQKTERLTHR
3D structure
PDB3h87 The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg(2+) ion in the active site and a putative RNA-binding site.
ChainA
Resolution1.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A D99 D117 D119 D98 D116 D118
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004518 nuclease activity
GO:0004540 RNA nuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0017148 negative regulation of translation

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Molecular Function

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Biological Process
External links
PDB RCSB:3h87, PDBe:3h87, PDBj:3h87
PDBsum3h87
PubMed23011806
UniProtP9WFB9|VAPC2_MYCTU Ribonuclease VapC2 (Gene Name=vapC2)

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