Structure of PDB 3h82 Chain A

Receptor sequence
>3h82A (length=115) Species: 9606 (Homo sapiens) [Search protein sequence]
EFKGLDSKTFLSEHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHAL
DSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQP
QCIMCVNYVLSEIEK
3D structure
PDB3h82 Principles of ligand binding within a completely buried cavity in HIF2alpha PAS-B
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 020 A H248 M252 A277 Y281 M289 Y307 M309 T321 C339 H14 M18 A43 Y47 M55 Y73 M75 T87 C105 MOAD: Kd=1.5uM
External links
PDB RCSB:3h82, PDBe:3h82, PDBj:3h82
PDBsum3h82
PubMed19950993
UniProtQ99814|EPAS1_HUMAN Endothelial PAS domain-containing protein 1 (Gene Name=EPAS1)

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