Structure of PDB 3h3t Chain A

Receptor sequence
>3h3tA (length=236) Species: 9606 (Homo sapiens) [Search protein sequence]
GTHRFVQKVEEMVQNHMTYSLQDVGGDANWQLVVEEGEMKVYRREVEENG
IVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLADNA
IIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVDHDSA
PLNNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGW
APASVLRAVAKREYPKFLKRFTSYVQEKTAGKPILF
3D structure
PDB3h3t Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer.
ChainA
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 16H A R442 E446 V472 W473 N504 A521 V525 Y553 Y576 F579 R80 E84 V110 W111 N142 A159 V163 Y191 Y214 F217
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3h3t, PDBe:3h3t, PDBj:3h3t
PDBsum3h3t
PubMed20036255
UniProtQ9Y5P4|CERT_HUMAN Ceramide transfer protein (Gene Name=CERT1)

[Back to BioLiP]