Structure of PDB 3gyt Chain A

Receptor sequence
>3gytA (length=242) Species: 6248 (Strongyloides stercoralis) [Search protein sequence]
YTLSEKDLKELDSIRDSFQCMNEPLDNDQQASTLAKKEHNPTDILNVMDI
TMRRLVKMAKRLGAFNEISEAGKFSLLKGGMIEMLTIRGVTVFNADKGVW
QTPVDGHSQISFNMFDKLRPDIKDTQKKGFLHFFNLLHSDVRKNDLAIDI
IVLMVLFDSKREGLVSQQDKETVEKLHRNYESLLHRYLYSIHKEEAEQRF
ASIPKALVALRKVAENAVTLFLGAGNTTEAASLPKEFFATNY
3D structure
PDB3gyt Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A K571 F585 K589 S743 E747 K60 F74 K78 S232 E236
BS02 DL4 A M559 I561 T562 T597 R599 G600 T613 F626 Q637 M48 I50 T51 T86 R88 G89 T102 F115 Q126
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