Structure of PDB 3gut Chain A

Receptor sequence
>3gutA (length=273) Species: 9606 (Homo sapiens) [Search protein sequence]
AYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTG
PGTVRISLVTKDPPHRPHPHELVGKDCRDGYYEADLCPDRSIHSFQNLGI
QCVKKRDLEQAISQRIQTNNNPFHVPIEEQRGDYDLNAVRLCFQVTVRDP
AGRPLLLTPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDK
VQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRV
SMQLRRPSDRELSEPMEFQYLPD
3D structure
PDB3gut Structural basis of HIV-1 activation by NF-kappaB--a higher-order complex of p50:RelA bound to the HIV-1 LTR.
ChainA
Resolution3.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y36 C38 E39 K122 R187 Y18 C20 E21 K104 R169 PDBbind-CN: Kd=1.5nM
BS02 dna A R33 R35 R41 R15 R17 R23 PDBbind-CN: Kd=1.5nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3gut, PDBe:3gut, PDBj:3gut
PDBsum3gut
PubMed19683540
UniProtQ04206|TF65_HUMAN Transcription factor p65 (Gene Name=RELA)

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