Structure of PDB 3gnn Chain A

Receptor sequence
>3gnnA (length=266) Species: 320372 (Burkholderia pseudomallei 1710b) [Search protein sequence]
TIDAVSPLFADISREYGAAFDAAIARNVADALAEDVGSGLVPDGAPRRAR
VIVREDAVLCGVPWFDAVVRAVDPSIEVDWRHREGDRMSADSTVCELRGP
ARALLTAERNALNFLQLLSGVASATRQYVDRIADTRARILDTRKTLPGLR
LAQKYAVRVGGGANQGVGEALDAAFALNVPVQIEVETLDQLRTALAHGAR
SVLLDNFTLDMMRDAVRVTEGRAVLEVSGGVNFDTVRAIAETGVDRISIG
ALTKDVRATDYSMRIV
3D structure
PDB3gnn Crystal structure of nicotinate-nucleotide pyrophosphorylase from Burkholderi pseudomallei
ChainA
Resolution2.25 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R115 K150 E211 D232
Catalytic site (residue number reindexed from 1) R109 K144 E184 D205
Enzyme Commision number 2.4.2.19: nicotinate-nucleotide diphosphorylase (carboxylating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V208 Q209 I210 V181 Q182 I183
Gene Ontology
Molecular Function
GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
Biological Process
GO:0009435 NAD biosynthetic process
GO:0019363 pyridine nucleotide biosynthetic process
GO:0034213 quinolinate catabolic process
Cellular Component
GO:0005737 cytoplasm

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External links
PDB RCSB:3gnn, PDBe:3gnn, PDBj:3gnn
PDBsum3gnn
PubMed
UniProtQ3JV59

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