Structure of PDB 3gm1 Chain A

Receptor sequence
>3gm1A (length=140) Species: 9606 (Homo sapiens) [Search protein sequence]
PTANLDRTDDLVYLNVMELVRAVLELKNELAQLPPEGYVVVVKNVGLTLR
KLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLAQQNAVTSL
SEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPA
3D structure
PDB3gm1 Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2
ChainA
Resolution2.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A P869 T870 N872 Y881 M885 L892 K988 P1 T2 N4 Y13 M17 L24 K120
BS02 peptide A K911 G914 L915 R918 N947 I954 R958 K43 G46 L47 R50 N79 I86 R90
Gene Ontology
Molecular Function
GO:0004713 protein tyrosine kinase activity
Biological Process
GO:0006468 protein phosphorylation
GO:0007172 signal complex assembly
Cellular Component
GO:0005925 focal adhesion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3gm1, PDBe:3gm1, PDBj:3gm1
PDBsum3gm1
PubMed19358827
UniProtQ14289|FAK2_HUMAN Protein-tyrosine kinase 2-beta (Gene Name=PTK2B)

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