Structure of PDB 3gl6 Chain A

Receptor sequence
>3gl6A (length=52) Species: 9606 (Homo sapiens) [Search protein sequence]
SVCAAQNCQRPCKDKVDWVQCDGGCDEWFHQVCVGVSPEMAENEDYICIN
CA
3D structure
PDB3gl6 Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.67: [histone H3]-trimethyl-L-lysine(4) demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D1621 K1622 V1623 D1624 W1625 V1626 Q1627 D1633 W1635 A1648 E1649 E1651 D14 K15 V16 D17 W18 V19 Q20 D26 W28 A41 E42 E44
BS02 ZN A S1608 C1619 S1 C12
BS03 ZN A C1610 C1615 C3 C8
BS04 ZN A C1628 C1632 C1655 C1658 C21 C25 C48 C51
External links
PDB RCSB:3gl6, PDBe:3gl6, PDBj:3gl6
PDBsum3gl6
PubMed19430464
UniProtP29375|KDM5A_HUMAN Lysine-specific demethylase 5A (Gene Name=KDM5A)

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