Structure of PDB 3gj7 Chain A

Receptor sequence
>3gj7A (length=201) Species: 9606 (Homo sapiens) [Search protein sequence]
PQVQFKLVLVGDGGTGKTTFVKRHLTGESEKKYVATLGVEVHPLVFHTNR
GPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHR
DLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYN
FEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQT
T
3D structure
PDB3gj7 Crystallographic and Biochemical Analysis of the Ran-binding Zinc Finger Domain.
ChainA
Resolution1.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K38 V40 T42 L43 W64 I81 Q82 K32 V34 T36 L37 W58 I75 Q76
BS02 GDP A G20 G22 K23 T24 T25 N122 K123 D125 I126 A151 K152 G14 G16 K17 T18 T19 N116 K117 D119 I120 A145 K146
BS03 MG A L31 E34 L25 E28
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003682 chromatin binding
GO:0003723 RNA binding
GO:0003924 GTPase activity
GO:0003925 G protein activity
GO:0005049 nuclear export signal receptor activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0019003 GDP binding
GO:0019904 protein domain specific binding
GO:0044877 protein-containing complex binding
GO:0045296 cadherin binding
GO:0045505 dynein intermediate chain binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0061676 importin-alpha family protein binding
GO:0070883 pre-miRNA binding
Biological Process
GO:0000054 ribosomal subunit export from nucleus
GO:0000055 ribosomal large subunit export from nucleus
GO:0000056 ribosomal small subunit export from nucleus
GO:0000070 mitotic sister chromatid segregation
GO:0000278 mitotic cell cycle
GO:0006259 DNA metabolic process
GO:0006606 protein import into nucleus
GO:0006611 protein export from nucleus
GO:0006913 nucleocytoplasmic transport
GO:0007052 mitotic spindle organization
GO:0007286 spermatid development
GO:0008104 protein localization
GO:0014070 response to organic cyclic compound
GO:0015031 protein transport
GO:0016032 viral process
GO:0021766 hippocampus development
GO:0030036 actin cytoskeleton organization
GO:0031503 protein-containing complex localization
GO:0032092 positive regulation of protein binding
GO:0035281 pre-miRNA export from nucleus
GO:0042307 positive regulation of protein import into nucleus
GO:0046039 GTP metabolic process
GO:0051301 cell division
GO:0061015 snRNA import into nucleus
GO:0071389 cellular response to mineralocorticoid stimulus
GO:1902570 protein localization to nucleolus
Cellular Component
GO:0000785 chromatin
GO:0001673 male germ cell nucleus
GO:0002177 manchette
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005643 nuclear pore
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005814 centriole
GO:0005829 cytosol
GO:0016020 membrane
GO:0030496 midbody
GO:0032991 protein-containing complex
GO:0036126 sperm flagellum
GO:0042470 melanosome
GO:0042565 RNA nuclear export complex
GO:0055037 recycling endosome
GO:0070062 extracellular exosome
GO:0090543 Flemming body

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3gj7, PDBe:3gj7, PDBj:3gj7
PDBsum3gj7
PubMed19505478
UniProtP62826|RAN_HUMAN GTP-binding nuclear protein Ran (Gene Name=RAN)

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