Structure of PDB 3ghn Chain A

Receptor sequence
>3ghnA (length=371) Species: 9606 (Homo sapiens) [Search protein sequence]
AQPGLYYSANEQCRVAFGPKAVACTDMCQALSCHTDPLDQSSCSRLLVPL
LDGTECGVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGV
VTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCARTD
GQPLSFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPS
GPREDGTLSLCVLGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGS
FTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRYVVAGKMSI
SPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRRY
GEEYGNLTRPDITFTYFQPKP
3D structure
PDB3ghn Production, crystallization and preliminary crystallographic analysis of an exosite-containing fragment of human von Willebrand factor-cleaving proteinase ADAMTS13
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.87: ADAMTS13 endopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUC A S399 C400 S95 C96
BS02 BGC A R398 C438 K440 F445 Q448 R94 C134 K136 F141 Q144
Gene Ontology
Biological Process
GO:0030198 extracellular matrix organization

View graph for
Biological Process
External links
PDB RCSB:3ghn, PDBe:3ghn, PDBj:3ghn
PDBsum3ghn
PubMed
UniProtQ76LX8|ATS13_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 13 (Gene Name=ADAMTS13)

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