Structure of PDB 3ghm Chain A

Receptor sequence
>3ghmA (length=369) Species: 9606 (Homo sapiens) [Search protein sequence]
AQPGLYYSANEQCRVAFGPKAVACMCQALSCHTDPLDQSSCSRLLVPLLD
GTECGVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVT
RRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQ
PLSFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGP
REDGTLSLCVLGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFT
AGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRYVVAGKMSISP
NTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRRYGE
EYGNLTRPDITFTYFQPKP
3D structure
PDB3ghm Production, crystallization and preliminary crystallographic analysis of an exosite-containing fragment of human von Willebrand factor-cleaving proteinase ADAMTS13
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.87: ADAMTS13 endopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A R398 C400 F445 Q448 R92 C94 F139 Q142
Gene Ontology
Biological Process
GO:0030198 extracellular matrix organization

View graph for
Biological Process
External links
PDB RCSB:3ghm, PDBe:3ghm, PDBj:3ghm
PDBsum3ghm
PubMed
UniProtQ76LX8|ATS13_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 13 (Gene Name=ADAMTS13)

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