Structure of PDB 3gh6 Chain A

Receptor sequence
>3gh6A (length=209) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
MDLYYRPGSAPCRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQ
HTIPTLHDHGFALWESRAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYF
DMGTLYKSFSEYYYPQIFLKKPANEENYKKIEVAFEFLNTFLEGQTYSAG
GDYSLADIAFLATVSTFDVAGFDFKRYANVARWYENAKKLTPGWEENWAG
CQEFRKYFD
3D structure
PDB3gh6 Structural evidence for conformational changes of Delta class glutathione transferases after ligand binding
ChainA
Resolution1.65 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S9
Catalytic site (residue number reindexed from 1) S9
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A S9 P11 Q39 H51 T52 I53 E65 S66 S9 P11 Q39 H51 T52 I53 E65 S66
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity
Biological Process
GO:0006749 glutathione metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3gh6, PDBe:3gh6, PDBj:3gh6
PDBsum3gh6
PubMed22475449
UniProtQ9VGA1

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