Structure of PDB 3gfd Chain A

Receptor sequence
>3gfdA (length=220) Species: 10090 (Mus musculus) [Search protein sequence]
SVEHIPFSHTRYPEQEMRMRSQEFYELLNKRRSVRFISSEHVPMEVIENV
IKAAGTAPSGAHTEPWTFVVVKDPDMKHKIREIIEEEEEINYMKRMGKRW
VTDLKKLRTNWIKEYLDTAPVLILIFKQVHGFNGKKKVHYYNEISVSIAC
GLLLAALQNAGLVTVTTTPLNCGPRLRVLLGRPSHEKLLVLLPVGYPSRD
ATVPDLKRKALDQIMVTVHH
3D structure
PDB3gfd Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands.
ChainA
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.21.1.1: iodotyrosine deiodinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN A R96 R97 S98 R100 T233 T234 T235 R31 R32 S33 R35 T166 T167 T168
BS02 IYR A E153 Y157 W165 L169 K178 E88 Y92 W100 L104 K113
BS03 FMN A P123 S124 G125 P58 S59 G60
BS04 IYR A G125 A126 Y208 G60 A61 Y141
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:3gfd, PDBe:3gfd, PDBj:3gfd
PDBsum3gfd
PubMed19436071
UniProtQ9DCX8|IYD1_MOUSE Iodotyrosine deiodinase 1 (Gene Name=Iyd)

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