Structure of PDB 3gdq Chain A

Receptor sequence
>3gdqA (length=376) Species: 9606 (Homo sapiens) [Search protein sequence]
GIAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGD
AAKNQVAMNPQNTVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKV
LVSYKGENKAFYPEEISSMVLTKLKETAEAFLGHPVTNAVITVPAYFNDS
QRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGERHVLIFDLGGGTFD
VSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQN
KRAVRRLRTACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRARFEELC
ADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNG
RDLNKSINPDEAVAYGAAVQAAILMG
3D structure
PDB3gdq Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D12 S18 K73 E177 D201
Catalytic site (residue number reindexed from 1) D7 S13 K68 E172 D193
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A T16 Y17 G203 G204 E270 K273 R274 S277 G340 G341 D368 T11 Y12 G195 G196 E262 K265 R266 S269 G332 G333 D360
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0140662 ATP-dependent protein folding chaperone

View graph for
Molecular Function
External links
PDB RCSB:3gdq, PDBe:3gdq, PDBj:3gdq
PDBsum3gdq
PubMed20072699
UniProtP34931|HS71L_HUMAN Heat shock 70 kDa protein 1-like (Gene Name=HSPA1L)

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