Structure of PDB 3gcm Chain A

Receptor sequence
>3gcmA (length=544) Species: 331111 (Escherichia coli O139:H28 str. E24377A) [Search protein sequence]
LNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAK
PGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRP
LFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGA
ARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQM
LGAVVFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNEALNARVAALAE
ARLSDAYRITDKQERYAQVDVIKSETIATLLAEDETLDENELGEILHAIE
KNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQAL
VTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGMVGSPKRREI
GHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALM
DAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDG
ISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPR
3D structure
PDB3gcm Crystal structure of Escherichia coli polynucleotide phosphorylase core bound to RNase E, RNA and manganese: implications for catalytic mechanism and RNA degradosome assembly.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.8: polyribonucleotide nucleotidyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E320 D322 M323 I324 G326 L327 V329 R330 T331 G332 V333 G528 V536 A540 E319 D321 M322 I323 G325 L326 V328 R329 T330 G331 V332 G527 V535 A539
BS02 peptide A V6 T17 E19 M22 M32 S34 D37 V5 T16 E18 M21 M31 S33 D36
BS03 MG A S437 I481 D492 S436 I480 D491
BS04 5GP A F77 F78 F76 F77
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004654 polyribonucleotide nucleotidyltransferase activity
Biological Process
GO:0006396 RNA processing
GO:0006402 mRNA catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3gcm, PDBe:3gcm, PDBj:3gcm
PDBsum3gcm
PubMed19327365
UniProtA7ZS61|PNP_ECO24 Polyribonucleotide nucleotidyltransferase (Gene Name=pnp)

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