Structure of PDB 3gbr Chain A

Receptor sequence
>3gbrA (length=341) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence]
MNINEILKKLINKSDLEINEAEELAKAIIRGEVPEILVSAILVALRMKGE
SKNEIVGFARAMRELAIKIDVPNAIDTAGTGGGGLGTVNVSTASAILLSL
VNPVAKHGNRAKSGSADVLEALGYNIIVPPERAKELVNKTNFVFLSAQYY
HPAMKNVANVRKTLGIRTIFNILGPLTNPANAKYQLMGVFSKDHLDLLSK
SAYELDFNKIILVYGEPGIDEVSPIGNTFMKIVSKRGIEEVKLNVTDFGI
SPIPIEKLIVNSAEDSAIKIVRAFLGKDEHVAEFIKINTAVALFALDRVG
DFREGYEYADHLIEKSLDKLNEIISMNGDVTKLKTIVVKSS
3D structure
PDB3gbr Activation of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus by removal of magnesium inhibition and acceleration of product release
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.18: anthranilate phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PRP A A78 G79 T80 G81 N89 V90 S91 T92 K106 G117 A78 G79 T80 G81 N89 V90 S91 T92 K106 G114
BS02 MN A D223 E224 D220 E221
BS03 MN A S91 E224 S91 E221
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004048 anthranilate phosphoribosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0000162 tryptophan biosynthetic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:3gbr, PDBe:3gbr, PDBj:3gbr
PDBsum3gbr
PubMed19385665
UniProtP50384|TRPD_SACS2 Anthranilate phosphoribosyltransferase (Gene Name=trpD)

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