Structure of PDB 3g8u Chain A

Receptor sequence
>3g8uA (length=79) Species: 10116 (Rattus norvegicus) [Search protein sequence]
SHMCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDK
IRRKNCPACRYRKCLQAGMNLEARKTKKK
3D structure
PDB3g8u DNA binding site sequence directs glucocorticoid receptor structure and activity.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A G458 S459 R466 R489 R496 G22 S23 R30 R53 R60 PDBbind-CN: Kd=0.89uM
BS02 dna A C450 H451 Y452 K465 R510 C14 H15 Y16 K29 R74 PDBbind-CN: Kd=0.89uM
BS03 ZN A C440 C443 C460 C4 C7 C24
BS04 ZN A C476 C482 C492 C495 C40 C46 C56 C59
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3g8u, PDBe:3g8u, PDBj:3g8u
PDBsum3g8u
PubMed19372434
UniProtP06536|GCR_RAT Glucocorticoid receptor (Gene Name=Nr3c1)

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