Structure of PDB 3g6m Chain A

Receptor sequence
>3g6mA (length=388) Species: 29856 (Clonostachys rosea) [Search protein sequence]
TGSINAVYFTNWGIYGRNFQPADLQASKILHVLYSFMNLRVDGTVYSGDT
YADLEKHYSDDSWNDIGTNAYGCVKQLYKLKKANRSLKIMLSIGGWTWST
NFPAAASTEATRATFAKTAVEFMKDWGFDGIDVDWEYPASETDANNMVLL
LQRVRQELDSYSATYANGYHFQLSIAAPAGPSHYNVLKLAQLGSVLDNIN
LMAYDYAGSWDSVSGHQTNLYPSTSNPSSTPFSTKAAVDAYIAAGVPASK
IILGMPIYGRAFVGTDGPGKPYSTIGEGSWESGIWDYKVLPKAGATVITD
SAAGATYSYDSSSRTMISYDTPDMVRTKVSYAKGLGLGGSMFWEASADKT
GSDSLIGTALSSMGSHDSTQNCLSYPNSKFDNIKNSLS
3D structure
PDB3g6m Crystal structure and mutagenesis analysis of chitinase CrChi1 from the nematophagous fungus Clonostachys rosea in complex with the inhibitor caffeine
ChainA
Resolution1.65 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D170 D172 E174 Y242
Catalytic site (residue number reindexed from 1) D132 D134 E136 Y204
Enzyme Commision number 3.2.1.14: chitinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CFF A F74 W134 D172 E174 M240 Y242 W381 F36 W96 D134 E136 M202 Y204 W343 MOAD: Ki=19.7mM
PDBbind-CN: -logKd/Ki=1.71,Ki=19.7mM
BS02 CFF A W134 D243 W248 W96 D205 W210 MOAD: Ki=19.7mM
PDBbind-CN: -logKd/Ki=1.71,Ki=19.7mM
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004568 chitinase activity
GO:0008061 chitin binding
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0005975 carbohydrate metabolic process
GO:0006032 chitin catabolic process
Cellular Component
GO:0005576 extracellular region

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Cellular Component
External links
PDB RCSB:3g6m, PDBe:3g6m, PDBj:3g6m
PDBsum3g6m
PubMed20829286
UniProtA9LI60

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