Structure of PDB 3g3r Chain A

Receptor sequence
>3g3rA (length=286) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
VRQTTKYWVHPDNITELKLIILKHLPVLVFNTNKEFEREDSAITSIYFDN
ENLDLYYGRLRKDEGAEAHRLRWYGGMSTDTIFVERKTHREDWTGEKSVK
ARFALKERHVNDFLKGKYTVDQVFAKMRKEGKKPMNEIENLEALASEIQY
VMLKKKLRPVVRSFYNRTAFQLPGDARVRISLDTELTMVREDNFDGVDRT
HKNWRRTDIGVDWPFKQLDDKDICRFPYAVLEVKLQTQLGQEPPEWVREL
VGSHLVEPVPKFSKFIHGVATLLNDKVDSIPFWLPQ
3D structure
PDB3g3r Catalytic core of a membrane-associated eukaryotic polyphosphate polymerase.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.4.1: ATP-polyphosphate phosphotransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ANP A R264 R266 K281 K294 Y359 R361 E426 S457 K458 R70 R72 K87 K100 Y165 R167 E232 S263 K264 MOAD: Kd=0.33uM
PDBbind-CN: -logKd/Ki=6.48,Kd=0.33uM
External links
PDB RCSB:3g3r, PDBe:3g3r, PDBj:3g3r
PDBsum3g3r
PubMed19390046
UniProtP47075|VTC4_YEAST Vacuolar transporter chaperone complex subunit 4 (Gene Name=VTC4)

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